Phase I & Pharmacokinetic Unit

After nearly 20 years of research experience and success in conducting clinical trials, Rainier Clinical Research Center has added a new full-service facility specializing in Phase I and Pharmacokinetic Research. This addition brings a new dimension to the existing clinical operation, with facilities to accommodate research subjects for extended or multiple overnight clinic stays in a safe and
comfortable environment. This clinic will help meet the ongoing industry need for sites that can facilitate rapid study initiation and deliver the patient populations that study sponsors are seeking. Rainier Clinical Research Center has conducted several hundred studies and maintains a very large database of subjects available for research for a wide spectrum of indications.

THE NEW PHASE I & PHARMACOKINETIC UNIT FEATURES

Six in-patient hospital beds for overnight stay On site drawing and processing lab with IACA certified staff Secured access drug room with -70° freezer Day clinic equipped with hospital recliners Satelite television Convenient location just 10 minutes from the Seattle-Tacoma International Airport Seven fully equipped exam room and procedure rooms Fax, DSL and wireless internet access Located appoximately 2 miles from a major medical center Patient lounge Full kitchen facilities

Staff of full-time, experienced Clinical Research Coordinators including Registered Nurses and Registered Dietitians Six monitor workstations with wireless internet access, copier, fax and phone Extensive experience with a wide variety of EDC software systems Extensive patient database of clinical trial participants in multiple therapeutic areas Full-time patient recruitment staff Administrative staff to manage budgets, contracts, and regulatory affairs Full-time IATA certified Phlebotomy and Lab Technicians Protocol design and scientific advisory support

CLINICAL TRIAL EXPERIENCE

Rainier Clinical Research Center, Inc. was established in 1989 by three board certified endocrinologists who had experience and interest in medical research and the goal of providing state-of-the-art care for their patients. Since its establishment, Rainier Clinical Research Center has conducted several hundred Phase I - IV domestic and international trials for both pharmaceutical and biotech companies. These studies include pharmaceutical compounds and medical devices.

WE HAVE EXPERIENCE IN THE FOLLOWING AREAS

Asthma Back Pain Carpal Tunnel Syndrome Chronic Obstructive Pulmonary Disease (COPD) Diabetes (Type I & II) Diabetes Testing & Montoring Devices Diabetes Insulin Delivery Devices Diabetic Neuropathy Healthy Normal Subjects Hypercholesterolemia Hyperlipidemia Hypertension Hypothyroid Insomnia Metabolic Syndrome Obesity Osteoarthritis Pain Management Preclinical Studies Raynaud's Phenomenon

RAINIER CLINICAL RESEARCH CENTER FOUNDERS AND PRINCIPAL INVESTIGATORS

All studies are conducted by Dr. Ronald Brazg, Dr. Allen Sussman and Dr. Leslie Klaff, the founders of Rainier Clinical Research Center.

Company Directors

Ronald Brazg, M.D., F.A.C.E. Clinical Assistant Professor of Medicine, Division of  Metabolism and Endocrinology, University of Washington. BIO | CURRICULUM VITAE     Ronald L. Brazg, M.D. is board certified in both Internal Medicine and Endocrinology and Metabolisrn. He has published research in diabetes and hyperlipidernia and is an Assistant Clinical Professor in the Departrnent of Medicine (Endocrinology) at the University of Washington Medical School. He is an active rnern ber of the Valley Medical Center research oversight cornrnittee and rnedical director of the diabetes education center.

Leslie Klaff, M.D., Ph.D., F.R.C.P., F.A.C.E. Clinical Professor of Medicine, Department of Endocrinology, Metabolism, and Nutrition, University of Washington. BIO | CURRICULUM VITAE     Leslie J. Klaff, M.D., Ph.D. F.R.C.P is board certified in both Internal Medicine and Endocrinology and Metabolisrn. He is currently a Clinical Professor of Medicine at the University of Washington. He was a co-investigator in the Diabetes Control and Cornplications Trial (DCCT) and is author and co-author of 43 papers and book chapters on diabetes related subjects.

Allen Sussman, M.D. Clinical Assistant Professor, University of Washington. Investigator, RCMC. BIO | CURRICULUM VITAE Allen M. Sussman, M.D. is board certified in both Internal Medicine and Endocrinology and Metabolisrn. He is an Assistant Clinical Professor at the University of Washington and has published research in diabetes and endocrinology. He has been a rnedical advisor to the Arnerican Diabetes Association and developed a statewide diabetes teen support prograrn.

CROs, BIOTECH & PHARMACEUTICAL COMPANIES WE HAVE WORKED WITH
OUR MISSION IS to provide an efficient, safe and professional environment for each one of our study participants and accurate uncompromised data for our study sponsors.
RAINIER CLINICAL RESEARCH CENTER works with the following pharmaceutical companies and clinical research organizations (CROs):
Abbott Diabetes Care	Kendle International Inc.
Abbott Laboratories	Kissei Pharma
Advanced Biologics	Knoll
Aegerion Pharmaceuticals, Inc.	Kos Pharmaceuticals
Alteon	MannKind Corporation
Alza Corporation	MediQuest
Amgen	Medpace
Amylin	Merck
ASTA Medica	Mitsubishi Pharma
Astellas Pharma Inc.	Neurobiological Technologies, Inc.
Astra Merck	Novartis
Astra Zeneca	Novo Nordisk
Avanir	Omnicare Clinical Research
Aventis	Parexel International
Barton and Polansky	Parke-Davis
Bayer	Pfizer
Becton Dickinson (BD)	Pharmacia Upjohn
BioNebraska	Pharmanet
BioStratum	Pliva
Boehringer Ingelheim	PPD Development
Bristol-Myers Squibb	PRA
Ciba Geigy	Procyte
Clinemetrics	Purdue Pharma
Clinical Research Management, Inc.	Quigley Pharma, Inc.
Clinical Trial Management Services, Inc.	Quintiles
ConjuChem	R.W. Johnson Pharmaceutical Research Institute
Covance	Regeneron Pharmaceuticals, Inc.
Curatek Pharmaceuticals	Restoragen
Dainippon Pharmaceutical Co., Ltd.	Rhone Poulenc Rorer
DepoMed	Sandoz
Eli Lilly	Sankyo Pharma Development
Epigenomics	Sanofi
Ergo Science	Sanofi-Aventis
Forest Labs	Sanwa Kagaku Kenkyusho Co Ltd
Genentech	Schwarz Pharma
Glaxo SmithKline	Sciele Pharma Inc.
GlaxoWellcome	Searle
Hoechst Marion Roussel	Shionogi USA Inc
Hoffman LaRoche	SmithKline Beecham
I-3 Research	Statprobe
ICON Clinical Research	Synergy Research
ICOS	Takeda America
INC Research	Takeda Global Research and Development Center
Ingenix	Teikoku Pharma USA
Integrium Cardiovascular Research	Therasense
Inveresk	United Biosource Corp.
Worldwide Clinical Trials	Wyeth Ayerst
Zeneca
For Further Information:
RAINIER CLINICAL RESEARCH CENTER conducts Phase I - IV studies with experienced medical professionals encompassing the following therapeutic areas:
Cardiology Devices Diabetes Diabetic Complications Endocrinology Gasteroenterology Hypertension Lipids Weight Loss Pain Podiatry Psychiatry Pulmonology
For a complete list of studies we have conducted see the Study Synopsis page.
RAINIER CLINICAL RESEARCH CENTER (RCRC) building is a 7000 square foot facility which features a combined clinical research center area and secure administrative office.   Fully furnished exam rooms Exam rooms are equipped with beds and televions to accommodate overnight in-patient studies Kitchen and cooking facilities Patient Lounge Processing lab with phlebotomy stations and abundant storage for lab supplies Refrigerated centrifuge Locked, temperature controlled drug storage room Dedicated offices and facilities for Clinical research Associates Internet access for study coordinates and CRAs Free parking for staff and study patients Easy access to local freeway Quick and easy access to Sea-Tac International Airport   CLINIC OPERATIONS RAINIER CLINICAL RESEARCH CENTER operates an on-site lab with full-time lab technicians. We also employ numerous full-time clinical research coordinators who bring a wide variety of experience, expertise and talent to our organization, including Registered Dietiticans and Registered Nurses. Our dedicated departments for recruitment and administrative affairs allow our clinical research coordinators to provide unsurpassed quality for patient care and clean, uncompromised data to our study sponsors. Protocol adherence is ensured by our ongoing quality assurance program.
PHASE I & PHARMACOKINETIC UNIT INFORMATION | Download